当院は昭和35年より地域の皆様に愛され支えられてまいりましたが、
2010年高齢化時代に伴い医療と介護両面で皆様の健康に
貢献させていただきたいと考え、新しい診療所に建て替え、
通所リハビリテーション・デイケア・ステップを開設いたしました。
今後は、池田内科医院と同様デイケアステップもよろしくお願い申し上げます。

当院は地域のかかりつけ医として、
皆様の健康と福祉に貢献することを使命とし ています。
患者様の話をよく聞き、十分な説明をし納得していただいて治療します。

• 昭和60年 関西医科大学卒業
• 昭和61年 静岡市立静岡病院 消化器内科
• 昭和64年 関西医科大学第3内科 入局
• 平成2年 道後温泉病院内科勤務　リウマチ認定医取得
• 平成4年 関西医科大学第1病理学教室 大学院
• 平成8年 関西医科大学第1病理学教室 学位取得
• 平成8年 ニューヨーク州North Shore University Hospital留学　HIV研究
• 平成9年 大阪府済生会泉尾病院消化器科医長
• 平成13年 愛徳会池田内科医院
• 平成14年 愛徳会池田内科医院 院長

ページトップへ

2002年より電子カルテでの診療を行っています。
また、2004年からはRS_Baseという優秀なファイリングシステムを導入し
すべての患者さまのデータをコンピュータで管理しています。
これにより一目で患者さまの過去の履歴を見ることができ
現在の診療に役立てることができます。

ページトップへ

私の専門である内視鏡、消化器内科を中心として、
内科全般から傷の処置、皮膚 科疾患、眼科疾患等の初期治療を行います。
また、香川大学神経内科の医師が パーキンソン病や
認知症をはじめとした神経内科の診療を行っています。

ページトップへ

2006年より在宅支援診療所の指定を受け、訪問診療をおこなっています。
医療と介護の訪問看護の指定も受けています。

ページトップへ

2010年2月1日より定員17名で”デイケア・ステップ”を新規開設しました。

ページトップへ

1. 【1】Changes in orientation of the major interlobar fissure in chronic liver diseases.

   Published date
   1991-12-06

   Journal
   Hepato-gastroenterology.38(3);228-30.

   Author
   Y Kubota, F Hashimoto, T Yamaguchi, S Kitagawa, K Tani, M Ogura, T Mizuno, T Katoh

   Affiliation
   Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan.

2. 【2】Focal segmental glomerular sclerosis, a type of intractable chronic glomerulonephritis, is a stem cell disorder.

   Published date
   1994-03-30

   Journal
   The Journal of experimental medicine.179(3);1053-8.

   Author
   M Nishimura, J Toki, K Sugiura, F Hashimoto, T Tomita, H Fujishima, Y Hiramatsu, N Nishioka, N Nagata, Y Takahashi

   Affiliation
   First Department of Pathology, Kansai Medical University, Osaka, Japan.

3. 【3】Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: possible explanation for the mechanism of tolerance induction by portal vein injection.

   Published date
   1994-08-09

   Journal
   European journal of immunology.24(7);1558-65.

   Author
   Y Zhang, R Yasumizu, K Sugiura, F Hashimoto, Y Amoh, Z Lian, Cherry, N Nishio, S Ikehara

   Affiliation
   First Department of Pathology, Kansai Medical University, Osaka, Japan.

4. 【4】Enhancing effects of cyclosporin A on hematopoietic progenitors: possible role of CD8+ T cells as negative regulators.

   Published date
   1994-10-20

   Journal
   Experimental hematology.22(10);947-53.

   Author
   F Hashimoto, K Sugiura, K Inoue, S Ikehara

   Affiliation
   First Department of Pathology, Kansai Medical University, Osaka, Japan.

   Abstract
   To elucidate the mechanism by which the administration of cyclosporin A (Cy A) improves a certain type of anemia, Cy A was orally administered to normal mice; hematopoietic activity, natural killer (NK) cell activity, and natural suppressor (NS) cell activity in the bone marrow (BM) were then examined. Hematopoietic colony formation was significantly enhanced by both 7-day and 21-day treatment with Cy A. Cy A did not, however, affect the total cell count or the numbers of macrophages, granulocytes, or B cells in the BM. Neither did Cy A affect the in vitro colony formation of the purified hematopoietic progenitors. These results suggest that Cy A acts on the negative regulators such as NK cells, NS cells, and CD8+ T cells. Since both NK and NS activity were also enhanced by Cy A treatment, these cells were not candidates. CD4+ or CD8+ T cells in the thymus, peripheral blood (PBL), and BM decreased as a result of the treatment. Therefore, to further examine the involvement of CD4+ or CD8+ T cells, hematopoietic colony formation was evaluated using bone marrow cells (BMCs) from mice purged of CD4+ and/or CD8+ cells. A significant enhancement of erythroid and multipotent colonies was observed in the BM of the CD8+ cell-purged mice. On the other hand, a significant enhancement of myeloid colonies was found in the BM of the CD4+ cell-purged mice. These findings suggest that single-positive T cells (particularly CD8+ T cells), which are diminished in number after Cy A treatment, are involved in the negative regulation of hematopoiesis.

5. 【5】Major histocompatibility complex restriction between hematopoietic stem cells and stromal cells in vivo.

   Published date
   1997-01-27

   Journal
   Blood.89(1);49-54.

   Author
   F Hashimoto, K Sugiura, K Inoue, S Ikehara

   Affiliation
   First Department of Pathology, Kansai Medical University, Osakã, Japan.

   Abstract
   Graft failure is a mortal complication in allogeneic bone marrow transplantation (BMT); T cells and natural killer cells are responsible for graft rejection. However, we have recently demonstrated that the recruitment of donor-derived stromal cells prevents graft failure in allogeneic BMT. This finding prompted us to examine whether a major histocompatibility complex (MHC) restriction exists between hematopoietic stem cells (HSCs) and stromal cells. We transplanted bone marrow cells (BMCs) and bones obtained from various mouse strains and analyzed the cells that accumulated in the engrafted bones. Statistically significant cell accumulation was found in the engrafted bone, which had the same H-2 phenotype as that of the BMCs, whereas only few cells were detected in the engrafted bones of the third-party H-2 phenotypes during the 4 to 6 weeks after BMT. Moreover, the BMCs obtained from the MHC-compatible bone showed significant numbers of both colony-forming units in culture (CFU-C) and spleen colony-forming units (CFU-S). These findings strongly suggest that an MHC restriction exists between HSCs and stromal cells.

6. 【6】Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.

   Published date
   1997-03-11

   Journal
   Journal of immunology (Baltimore, Md. : 1950).2456-63.

   Author
   N Oyaizu, Y Adachi, F Hashimoto, T W McCloskey, N Hosaka, N Kayagaki, H Yagita, S Pahwa

   Affiliation
   Department of Pediatrics, North Shore University Hospital-Cornell University Medical College, Manhasset, NY 11030, USA.

7. 【7】Modulation of Bcl-2 protein by CD4 cross-linking: a possible mechanism for lymphocyte apoptosis in human immunodeficiency virus infection and for rescue of apoptosis by interleukin-2.

   Published date
   1997-08-07

   Journal
   Blood.90(2);745-53.

   Author
   F Hashimoto, N Oyaizu, V S Kalyanaraman, S Pahwa

   Affiliation
   Department of Pediatrics, North Shore University Hospital-New York University School of Medicine, Manhasset 11030, USA.

   Abstract
   We have previously demonstrated that CD4 cross-linking (CD4XL) results in apoptosis of CD4+ T cells and augmentation of Fas antigen (CD95, APO-1) expression in CD4+ and CD8+ T cells. Here we demonstrate that CD4XL mediated by both, anti-CD4 monoclonal antibody (MoAb) or human immunodeficiency virus (HIV) envelope protein gp120 reduces the expression of the proto-oncogene Bcl-2 in CD4+ T cells, but not in CD8+ T cells, concurrently with the induction of CD4+ T cell-apoptosis. Additionally, the Bcl-2dim population expressed high levels of Fas antigen. Bax, an antagonist of Bcl-2, was brightly expressed even in the Bcl-2dim population. Addition of interleukin (IL)-2 rescued CD4+ T cells from CD4XL-induced Bcl-2 downmodulation and apoptosis induction. These results support the hypothesis that CD4 ligation by HIV-1 envelope protein in vivo in HIV-infected patients selectively reduces Bcl-2 protein in CD4+ T lymphocytes, thereby facilitating Fas/Fas-ligand triggered apoptosis; furthermore the findings reported expand the rationale for use of IL-2 in HIV disease.

8. 【8】Induction of donor-specific T cell anergy by portal venous injection of allogeneic cells.

   Published date
   1998-02-09

   Journal
   Immunobiology.197(5);460-77.

   Author
   K Sugiura, K Kato, F Hashimoto, T Jin, Y Amoh, Y Yamamoto, H Morita, K Okumura, S Ikehara

   Affiliation
   First Department of Pathology, Kansai Medical University, Osaka, Japan.

9. 【9】An autopsy case of giant cell myocarditis probably due to a non-steroidal anti-inflammatory drug.

   Published date
   2001-02-22

   Journal
   Pathology international.51(2);113-7.

   Author
   Y Adachi, R Yasumizu, F Hashimoto, Y Otsuka, A Okamura, Y Kato, H Oyaizu, K Ikebukuro, S Fukuhara, Y Nakai, S Ikehara

   Affiliation
   First Department of Pathology, Kansai Medical University, Osaka, Japan.

10. 【10】膵管癒合不全を伴った自己免疫性膵炎の1例

    辻上幸司1), 若山克則1), 福田直子1), 手束一博1), 小田修治1), 橋本不動志2)

    国立善通寺病院・消化器科1), 池田内科医院2)

    日本消化器病学会雑誌 103(suppl-2.2): 979-979, 2006.

11. 【11】短期間に再発を繰り返した胃ポリープの1例

    藤井寿仁*, 橋本不動志, 門田洋一, 金澤威夫, 松本隆之, 澤村隆也**

    *大阪府済生会中津病院消化器内科, **大阪府済生会泉尾病院消化器内科

    綜合臨牀 48(1): 197-200, 1999.

12. 【12】RAにおける続発性アミロイドーシス

    橋本不動志, 高杉潔

    道後温泉病院リウマチ科

    医学のあゆみ 161(9): 656-659, 1992.

13. 【13】レーザー内視鏡治療を施行した早期胃癌症例の検討

    高橋好朗, 天羽康雄, 橋本不動志, 田中俊夫, 渥美清, 村上隼夫

    市立静岡病院消化器科

    日本レーザー医学会誌 10(4): 53-53, 1990.

ページトップへ